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g00380: Sonic hedgehog

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Darkfield Expression Patterns

Age E11
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Age E15
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Age P7
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Click on the Images above to view higher resolution Darkfield Expression Pattern

Gene Information

Description:
sonic hedgehog (pubmed)
Accession:
NM_009170.3 (GI Link)
Unigene:
Mm.57202
Official Gene Symbol:
Shh
Alternate Gene Symbols/Aliases:
9530036O11Rik, Dsh, Hhg1, Hx, Hxl3, M100081
Gene Id:
20423
Function: patched binding, protein binding, peptidase activity, hydrolase activity, laminin-1 binding

Process: angiogenesis, angiogenesis, angiogenesis, patterning of blood vessels, vasculogenesis, metanephros development, ureteric bud branching, cell fate specification, cell fate specification, neural crest cell migration, kidney development, hair follicle development, positive regulation of neuroblast proliferation, osteoblast development, proteolysis, cell communication, signal transduction, smoothened signaling pathway, smoothened signaling pathway, positive regulation of hh target transcription factor activity, positive regulation of hh target transcription factor activity, cell-cell signaling, multicellular organismal development, pattern specification process, pattern specification process, neuroblast proliferation, axon guidance, axon guidance, central nervous system development, salivary gland morphogenesis, hindgut morphogenesis, heart development, androgen metabolic process, positive regulation of cell proliferation, positive regulation of cell proliferation, positive regulation of cell proliferation, embryonic development, organ morphogenesis, anterior/posterior pattern formation, dorsal/ventral pattern formation, oligodendrocyte development, intein-mediated protein splicing, spinal cord dorsal/ventral patterning, smoothened signaling pathway in regulation of granule cell precursor cell proliferation, smoothened signaling pathway in regulation of granule cell precursor cell proliferation, positive regulation of granule cell precursor proliferation, telencephalon regionalization, regulation of proteolysis, lung development, lung development, embryonic limb morphogenesis, embryonic limb morphogenesis, negative regulation of cell migration, male genitalia development, prostate gland development, forebrain development, midbrain development, hindbrain development, hindbrain development, hair follicle morphogenesis, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, regulation of cell proliferation, negative regulation of T cell proliferation, negative regulation of protein catabolic process, positive regulation of protein import into nucleus, odontogenesis of dentine-containing teeth, embryonic digit morphogenesis, camera-type eye development, camera-type eye development, myoblast differentiation, regulation of transcription, negative regulation of cell differentiation, negative regulation of cell differentiation, positive regulation of transcription from RNA polymerase II promoter, negative regulation of alpha-beta T cell differentiation, cell development, embryonic organ development, developmental growth, embryonic morphogenesis, anatomical structure formation, neuron fate commitment, branching morphogenesis of a tube, anatomical structure development, striated muscle cell differentiation, striated muscle cell differentiation, Bergmann glial cell differentiation

Component: extracellular region, extracellular space, cell surface, membrane, lipid raft

Chromosome:
5
Cytogenetic Location:
B1
Genetic Location:
16.0 cM
View Entire Probe Sequence


Human Ortholog

SHH, NP_000184.1, Gene ID: 6469


Additional Information in Other Databases

Direct Links

  • Mouse Genome Informatics (MGI)
  • Online Mendelian Inheritance in Man (OMIM)
  • Mutant Mouse Regional Resource Centers (MMRRC)
  • GENSAT at NCBI
  • GENSAT at Rockefeller.edu

  • Rockefeller BAC Status : BAC data deployed in the public database

    Indirect Links

  • GNF SymAtlas
  • GeneNetWork WebQTL


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