Navigating the database
Visitors can browse through the images using the gene list icon located in
page headings above. The gene list can be alphabetized according to Genbank
accession #, Gene Identification and Description, or by the official Gene symbol
in order from A-Z or Z-A. Specific genes can be identified using the search
icon located in the headings. Visitors can search for specific genes, spatial
and temporal expression patterns, keywords, chromosomal location, and gene ontology
terms. Individual accounts can be established free of charge that allow account
holders to save collected images for future visits to the website.
Viewing images in the Database
There are several ways to view the images.
1. The entire set of thumbnail size images for each gene can be browsed on
the main gene page
2. A single darkfield image can be viewed side-by-side with nearest reference
cresyl violet stained section
3. A large image can be viewed on the monitor or downloaded as a high resolution
photographic quality image (300 dpi) image at 5.5x3.607 inches.
4. Selected images can be saved to a gene expression viewer that allows side-by-side
comparison of expression patterns.
Genes in the Database
The genes represented in this database are members of a variety of gene families
with wide distribution in gene ontology and chromosomal location. Many genes
were selected by a broad panel of neuroscience experts in the fields of Development,
Neurodegeneration, Receptors/Channels and Cognitive Neuroscience based on their
interest to the research community. In addition, many genes in the database
have no known function in the nervous system, or are completely uncharacterized.
We have included these uncharacterized genes to facilitate new discoveries and
to stimulate novel research directions in neurobiology. We found that 65% of
the genes in the database, regardless of their origin, display a “patterned”
distribution of mRNA in either the temporal or spatial dimension. We are continually
adding new genes to the database with the ultimate goal of representing the
majority of genes that are expressed in the developing and adult brain.